Cementless Total Knee Arthroplasty Market By Component Type (Femoral, Tibial, Patellar); By Material (Titanium Alloys, Cobalt-Chromium Alloys, Polyethylene, Ceramics); By End User (Hospitals, Ambulatory Surgical Centers, Specialty Clinics); By Geography, Segment Revenue Estimation, Forecast, 2024–2030

Introduction And Strategic Context

The Global Cementless Total Knee Arthroplasty (TKA) Market will witness a robust CAGR of 7.5 % , valued at $2.87 billion in 2024 , and is expected to appreciate and reach $ 4.38 billion by 2030 , confirms Strategic Market Research.

 

Cementless total knee arthroplasty is a surgical solution for replacing damaged knee joints without using bone cement. Instead, it relies on biological fixation, allowing bone tissue to grow into the porous surface of the implant. This approach is strategically significant in orthopedic surgery as it enables better long-term outcomes, especially for younger and more active patients. By leveraging advancements in biomaterials and 3D printing, cementless TKA is rapidly transitioning from a niche option to a mainstream orthopedic practice.

 

Several macroeconomic and clinical drivers are fueling the cementless TKA market in the 2024–2030 period:

• Rising prevalence of osteoarthritis and rheumatoid arthritis due to aging demographics and lifestyle-related risk factors.

• Accelerated shift towards value-based healthcare and long-term implant survivorship, reducing revision surgery rates.

• Technological innovations in implant design, including porous titanium and trabecular metal, improving osseointegration.

• Growth in outpatient and ambulatory surgical centers (ASCs) adopting minimally invasive joint replacement protocols.

Governments and payers are encouraging earlier interventions and faster recovery pathways, which align well with cementless systems. Moreover, the ongoing trend toward personalized implants , aided by imaging and digital planning tools, further elevates the potential of cementless TKA solutions to become standard care.

 

The stakeholder ecosystem includes:

• Orthopedic OEMs (original equipment manufacturers) developing implants and instruments

• Hospitals and ambulatory surgical centers (ASCs)

• Regulatory agencies approving device innovations

• Investors targeting high-growth surgical technologies

• Payers and insurance providers incentivizing cost-effective long-term outcomes

Experts indicate a clear pivot in orthopedic care strategy toward biologically integrated, long-lasting implant systems. Cementless TKA—once reserved for young patients—is now being adopted across wider age brackets due to clinical success rates and reduced complications associated with cement failure.

 

Market Segmentation And Forecast Scope

To provide strategic clarity, the cementless total knee arthroplasty market can be segmented across four major dimensions:

By Component Type

• Femoral Component

• Tibial Component

• Patellar Component

Among these, the femoral component dominates the revenue share in 2024 due to its critical role in load distribution and its reliance on durable, porous materials for bone in-growth. However, the tibial component is projected to be the fastest-growing segment through 2030, driven by innovations in monoblock designs and improved fixation interfaces.

 

By Material

• Titanium Alloys

• Cobalt-Chromium Alloys

• Polyethylene

• Ceramics

Titanium alloys hold the majority share in 2024, appreciated for their lightweight structure and high osseointegration potential. Materials with trabecular architecture or hydroxyapatite coatings are gaining favor among surgeons for superior bone bonding and longevity.

 

By End User

• Hospitals

• Ambulatory Surgical Centers (ASCs)

• Specialty Orthopedic Clinics

Hospitals dominate the market in 2024 with over 62% share , given their advanced infrastructure and access to high-volume surgical caseloads. However, ASCs are expected to exhibit the fastest growth , as cost-conscious procedures and short-stay arthroplasty protocols become more mainstream.

 

By Region

• North America

• Europe

• Asia Pacific

• Latin America

• Middle East & Africa

North America remains the market leader due to early adoption, favorable reimbursement, and a strong orthopedic ecosystem. However, Asia Pacific is the fastest-growing region , fueled by rising arthroplasty awareness, medical tourism, and the expansion of orthopedic infrastructure in countries like India, China, and South Korea.

This segmentation framework supports a targeted analysis of growth zones, unmet needs, and investment opportunities in the global cementless TKA space.

 

Market Trends And Innovation Landscape

The cementless total knee arthroplasty market is undergoing a significant transformation driven by cross-disciplinary innovations in biomechanics , material science , and digital surgical planning . From implant microgeometry to AI-powered personalization, this space is rich with advancements set to redefine orthopedic standards over the coming decade.

1. Material and Surface Engineering Innovations

Modern cementless implants increasingly use trabecular metal , porous titanium , and hydroxyapatite coatings to enhance osseointegration. These surfaces mimic cancellous bone structure, allowing natural bone in-growth and reducing micromotion.

Emerging 3D printing capabilities are now enabling custom lattice structures for femoral and tibial components. According to orthopedic biomaterials experts, these new designs are achieving earlier fixation stability and faster post-op recovery times compared to traditional cemented techniques.

 

2. Patient-Specific Instrumentation (PSI) and Digital Twin Surgery

The integration of digital pre-operative planning and patient-specific cutting guides is accelerating the adoption of cementless TKA. Surgeons can now simulate implant fit, load transfer, and alignment digitally—minimizing intraoperative guesswork.

New platforms using digital twin models are allowing surgeons to map patient bone morphology with high fidelity, making cementless fixation more reliable, even in complex anatomies.

 

3. AI, Robotics, and Navigation Systems

AI-enabled surgical robots are increasingly being used to optimize implant positioning, limb alignment , and soft-tissue balancing —three critical success factors in cementless procedures. Robotic precision reduces implant misfit, which is particularly important for achieving solid biological fixation.

Companies are also exploring real-time intraoperative navigation tools with sensor feedback to assess bone quality and decide dynamically whether cementless fixation is suitable.

 

4. Rapid Recovery Protocols & Same-Day Discharge

Enhanced Recovery After Surgery (ERAS) programs are pushing cementless implants into outpatient and ASC settings , thanks to their shorter surgical time and reduced post-op complications. Patients benefit from faster ambulation, lower infection rates, and improved satisfaction scores.

Clinicians are reporting that cementless TKA, when integrated with robotic guidance and recovery protocols, is reducing overall length of stay by up to 30% in optimized centers .

 

5. M&A and Technology Collaborations

Recent years have seen a flurry of strategic partnerships between orthopedic OEMs and digital health firms. For example, firms specializing in AI-guided surgery have been acquired by legacy implant companies to integrate intelligent feedback loops into their systems.

Meanwhile, startups in bioceramic coatings and resorbable scaffolds are gaining attention for next-generation implant surfaces.

As technological convergence accelerates, the cementless TKA market is evolving from an implant business into a hybrid of hardware, software, and analytics—paving the way for smart, personalized joint care.

 

Competitive Intelligence And Benchmarking

The cementless total knee arthroplasty market features a dynamic and competitive landscape with a mix of multinational orthopedic giants and high-tech innovators. Each player is deploying distinct strategies around product innovation , geographic reach , and surgical platform integration to capture the expanding demand for cementless procedures.

Here are some of the key companies driving market momentum:

Zimmer Biomet

A global leader in orthopedics , Zimmer Biomet continues to dominate the cementless knee segment with its porous-coated femoral and tibial implants. The company focuses heavily on digitally connected surgical platforms and has integrated its Rosa Robotics system with cementless-compatible knee implants. It also promotes fast-track protocols aligned with Enhanced Recovery After Surgery (ERAS) pathways.

 

Stryker

Stryker has made significant strides through its Triathlon® Tritanium cementless system , known for its 3D-printed porous structures. The company is uniquely positioned with its Mako robotic platform , which provides real-time feedback and planning tools for precise implant positioning—crucial for successful cementless fixation. Stryker is also actively expanding its footprint in Asia-Pacific and Latin America through localized production and surgeon training centers .

 

DePuy Synthes (Johnson & Johnson)

DePuy Synthes emphasizes evidence-based outcomes and modular implant systems. With a robust global presence, the company leverages its ATTUNE Cementless Knee System —noted for promoting anatomical bone in-growth and patient stability. DePuy’s strategy includes deep collaborations with teaching hospitals to refine cementless surgical techniques and outcomes monitoring.

 

Smith+Nephew

Smith+Nephew is carving a niche with its OXINIUM™ technology and VERILAST bearing surfaces, offering reduced wear rates in cementless applications. Its investment in ambulatory surgical center partnerships is creating new demand, particularly in North America. The company also bundles cementless implants with advanced wound care and digital surgery tools for full-cycle care solutions.

 

Exactech

A fast-growing challenger, Exactech is known for its Truliant ® cementless system and real-time intraoperative kinematic assessments. The company’s platform includes machine learning algorithms to guide alignment and pressure distribution, targeting younger, active patients. It focuses on regional partnerships and education initiatives, particularly in community-based hospitals.

 

Aesculap (B. Braun)

Aesculap offers a line of cementless systems built on German engineering precision, with a focus on long-term implant survivorship . It caters to high-volume surgical centers in Europe and Asia, emphasizing cost-effectiveness and durability.

 

MicroPort Orthopedics

MicroPort brings strength in modular implant systems and a vertically integrated supply chain, offering a price-competitive edge in emerging markets. It has ramped up investment in research for biologically enhanced porous surfaces , and is expanding into Middle East and Latin America aggressively.

Across the board, companies are moving beyond device manufacturing into integrated care models—blending implants with AI, robotics, and remote monitoring tools to deliver smarter, longer-lasting outcomes in cementless total knee replacements.

 

Regional Landscape And Adoption Outlook

The global cementless total knee arthroplasty market demonstrates highly uneven adoption across regions, largely influenced by differences in surgical expertise, reimbursement policies, healthcare infrastructure, and patient demographics. While North America leads the innovation frontier, other regions are catching up quickly, driven by medical tourism, value-based care models, and increasing arthroplasty literacy.

North America

North America commands the largest share of the global market, contributing over 38% of total revenues in 2024 . The U.S. leads the region due to:

• A mature orthopedic ecosystem

• High per capita procedural volumes

• Early adoption of robotic-assisted surgery

• Favorable reimbursement for outpatient arthroplasty

The growing shift to ambulatory surgical centers (ASCs) is a defining trend, particularly as insurers support shorter hospital stays and cementless implants support rapid mobilization.

Canada is also advancing in cementless TKA adoption, supported by government-backed initiatives promoting minimally invasive orthopedic surgeries and implant longevity.

 

Europe

Europe holds a stable and technology-forward market, with Germany, France, and the UK as front-runners. Regional characteristics include:

• Well-established public healthcare systems

• Strong adoption of evidence-based implants

• Favorable funding for geriatric orthopedic care

Germany is particularly notable for pioneering porous coating technologies and supporting rigorous clinical trials on implant survivorship. Meanwhile, the UK’s National Joint Registry (NJR) plays a crucial role in collecting long-term data on cementless outcomes.

European surgeons are often conservative in implant adoption, but the growing body of long-term success data is steadily shifting practices toward cementless systems.

 

Asia Pacific

Asia Pacific is the fastest-growing region , expected to expand at a CAGR above 9% between 2024 and 2030. Key drivers include:

• Rapid expansion of urban healthcare infrastructure

• Government subsidies for arthroplasty procedures in India and China

• Rising awareness among middle-aged populations

India and China are hotbeds for medical tourism, where cementless systems are offered as premium, long-lasting alternatives. South Korea leads in digital planning adoption and has integrated cementless knees in public and private orthopedic hospitals alike.

Regional OEMs and global players are investing heavily in surgeon training and localized manufacturing to accelerate penetration into tier 2 and tier 3 cities.

 

Latin America

Adoption in Latin America remains modest but rising steadily. Brazil is the dominant market, followed by Mexico and Argentina , supported by:

• Public-private partnerships in orthopedic infrastructure

• Growing population of middle-income patients seeking joint care

• Government-led investments in specialty surgery centers

Challenges include inconsistent reimbursement systems and low penetration of robotic platforms that support cementless techniques.

 

Middle East & Africa

This region represents a white space opportunity with relatively low procedural volumes but growing institutional investments in orthopedic care. Gulf countries (UAE, Saudi Arabia) are attracting top surgical talent and establishing centers of excellence.

The region’s medical tourism sector, particularly in the UAE, is drawing international patients for advanced procedures like cementless TKA, creating a foothold for global OEMs.

Overall, the regional landscape illustrates a two-speed market : developed economies focus on optimization and robotic enhancement, while emerging markets emphasize accessibility and affordability. Both pathways support the long-term growth of cementless total knee arthroplasty worldwide.

 

End-User Dynamics And Use Case

The adoption of cementless total knee arthroplasty (TKA) varies significantly across end-user environments, shaped by procedural complexity, patient demographics, and institutional priorities. From high-volume tertiary hospitals to nimble ambulatory surgical centers (ASCs), the demand for cementless implants is increasing due to better long-term outcomes, reduced post-op complications, and alignment with fast-recovery protocols.

Hospitals

Hospitals , particularly tertiary and teaching hospitals, represent the largest consumer base for cementless knee systems. These institutions are equipped with:

• Robotic-assisted surgical platforms

• Full orthopedic teams for complex joint cases

• In-house rehabilitation facilities for post-op care

Academic hospitals also serve as early adopters and clinical trial sites for novel cementless designs, supporting long-term outcome registries.

However, adoption is often gated by the surgeon’s preference, access to robotic guidance, and case mix (e.g., younger, active patients vs. elderly with osteoporosis).

 

Ambulatory Surgical Centers (ASCs)

ASCs are rapidly emerging as a high-growth end user , driven by:

• Minimally invasive, short-stay protocols

• Surgeons opting for faster turnaround times

• Payers incentivizing outpatient procedures for cost savings

Cementless systems are well-suited for ASCs due to their quicker fixation process, reduced need for cement handling time, and enhanced intraoperative efficiency.

As robotic platforms become more compact and affordable, their integration into ASC settings is accelerating, making cementless knee arthroplasty even more viable in same-day discharge environments.

 

Specialty Orthopedic Clinics

These clinics, often linked to hospital systems or operating as independent centers , are focused on elective joint procedures . They are ideal candidates for cementless systems when treating:

• Younger, athletic patients

• Revision or re-operation cases where cementless fixation offers biomechanical advantages

• Patients preferring a more “natural” biologic healing process

Surgeons in these settings report growing patient interest in cementless options, citing fewer concerns over cement breakdown or thermal necrosis associated with cemented techniques.

 

Real-World Use Case

A tertiary hospital in Seoul, South Korea , implemented a digitized workflow combining AI-based preoperative planning and cementless knee systems for patients under 60. Over a 12-month period, the orthopedic team conducted 180 cementless TKA procedures using robotic guidance and patient-specific implants. Outcomes included:

• A 27% reduction in average surgical time

• Early mobilization within 6 hours post-surgery in 72% of cases

98.6% implant stability at 6-month follow-up, confirmed via radiostereometric analysis

This case illustrates how cementless solutions, when integrated with advanced tools and recovery protocols, can optimize both procedural efficiency and patient satisfaction.

 

Recent Developments + Opportunities & Restraints

Recent Developments (Last 2 Years)

• Zimmer Biomet launched an expanded line of cementless knee solutions integrated with its Rosa Robotics platform, aiming to streamline digital planning with biologic fixation implants.

• Stryker received FDA clearance for updates to its Triathlon Tritanium Cementless System , enabling broader compatibility with same-day discharge protocols.

• Exactech introduced its AI-based intraoperative guidance software , assisting surgeons in real-time bone quality assessment during cementless TKA.

• Smith+Nephew entered into strategic agreements with outpatient surgery networks to expand access to cementless knees in ambulatory settings.

• MicroPort Orthopedics announced an R&D expansion focused on next-gen porous implant surfaces , aiming to increase adoption in Southeast Asia and Latin America.

 

Opportunities

• Surge in Younger Arthroplasty Patients The rising incidence of knee osteoarthritis in patients under 60 is expanding the eligible pool for biologically integrated, cementless solutions.

• Integration with Robotic Surgery and AI As AI and robotic platforms become more affordable and portable, their compatibility with cementless systems unlocks broader application in both hospitals and ASCs.

• Market Expansion in Emerging Economies Rapid infrastructure development in Asia Pacific, Latin America, and the Middle East offers a significant white space for cementless TKA growth—especially where patients seek longevity and mobility.

 

Restraints

• High Upfront Implant and Technology Costs Cementless systems, especially those paired with navigation or robotic tools, carry a higher upfront cost than cemented alternatives—posing a barrier in cost-sensitive health systems.

• Surgeon Learning Curve and Skepticism Some orthopedic surgeons, especially in regions with fewer continuing education resources, remain hesitant to switch from traditional cemented methods due to familiarity and training gaps.

While challenges exist, the momentum for cementless total knee arthroplasty is clearly building—driven by converging forces of innovation, economics, and demographic demand.

 

7.1. Report Coverage Table

Report Attribute	Details
Forecast Period	2024 – 2030
Market Size Value in 2024	USD 2.87 Billion
Revenue Forecast in 2030	USD 4.38 Billion
Overall Growth Rate	CAGR of 7.5% (2024 – 2030)
Base Year for Estimation	2024
Historical Data	2019 – 2023
Unit	USD Million, CAGR (2024 – 2030)
Segmentation	By Component Type, By Material, By End User, By Geography
By Component Type	Femoral Component, Tibial Component, Patellar Component
By Material	Titanium Alloys, Cobalt-Chromium Alloys, Polyethylene, Ceramics
By End User	Hospitals, Ambulatory Surgical Centers, Specialty Clinics
By Region	North America, Europe, Asia-Pacific, Latin America, Middle East & Africa
Country Scope	U.S., UK, Germany, China, India, Japan, Brazil, UAE, etc.
Market Drivers	- Rising demand in younger populations - Robotic-assisted precision - Emergence of outpatient arthroplasty
Customization Option	Available upon request